World-class facilities

In 2016, we completed a design and build programme of new bioprocessing and laboratory facilities at our sites in Oxford, UK. These complement our existing capabilities, significantly extending our capacity and providing dual sourcing to further enhance supply chain robustness.  We also received regulatory approval from the UK Medicines and Healthcare products Regulatory Agency (MHRA) for GMP manufacture and release of bulk drug material for investigational medicinal products at the facilities, which are fully operational.  

State-of-the-art bioprocessing

Our bespoke biomanufacturing suites total 1,200m2 (12,917ft2) across three independent clean rooms, with potential for further expansion as required.  We operate both cell factories and next generation single-use 200 litre bioreactors in dedicated production suites. These provide capacity for our internal programmes, as well as development and production for our partners, including our flagship collaboration with Novartis on its lead CAR-T therapies.

Purpose-built laboratories

Our bioprocessing capabilities are supported by our process development, analytics and quality laboratories. Our GMP/GLP accredited facilities include:

• Bio-safety category three (BSL-C3) labs

• Tissue culture and cell engineering laboratories

• Process R&D labs

• QC chemistry and microbiology labs

• Analytical services and clinical analysis laboratories

• PCR, HPLC and FACS suites


Download our bioprocessing brochure